(StatePoint) In summer you want your skin to look and feel its best. But all that extra exposure introduces more risks of irritation, rashes and bites. “If you’re careful and prepared, you can reduce your risk for certain ailments as well as limit your discomfort,” says Dr. Vishakha Gigler, a board certified dermatologist in Encinitas, Ca. Here’s a handy guide your family can use to avoid and treat skin woes, such as itching and pain, most common in the summer months. • Prevent sunburn by always applying a high SPF sunblock before sun exposure. If possible, wait 15 minutes before walking outdoors. Don’t forget to reapply after excessive sweating or water exposure. • If you do get burned, relieve inflammation and redness by applying ice in a milk-soaked face cloth to affected areas for five to 10 minutes. • Protect your pucker and treat dry, chapped lips with shea butter or beeswax lip balm with SPF, which moisturize while providing sun protection. • Drink plenty of cold water to cool down and hydrate your body and skin. • Mosquitoes dwell in areas near standing water and are attracted to hot skin temperatures. Keep skin cool and eliminate standing water from your yard. Also, be mindful that mosquitoes are most active at dusk. • Do you live near a wooded area? Are you taking advantage of the season to go hiking or camping? Avoid exposure to poisonous plants by wearing long pants, long shirts and boots, along with a topically applied ivy block barrier cream to prevent getting a poison ivy or oak rash breakout. • When prevention fails, adults and children two years and older can treat bug bites and other itchy summer skin flare-ups with a dermatologist- recommended, over-the-counter non- steroid-based topical treatment, such as TriCalm. A highly effective itch relief gel, TriCalm is five times more effective than hydrocortisone 1% at reducing itch, and does not have side effects like skin thinning and stretch marks. Summer fun and sun can have its drawbacks, especially where your skin is concerned. For a more comfortable season, be prepared to prevent and treat itches, burns and skin flare-ups.
(StatePoint) You may not realize it, but your sugar consumption has likely increased over the last several years. Beyond what you add to your coffee or the occasional sweet treat, you may be getting hidden sugar from an array of processed foods, such as ketchup and salad dressing. Even conventional baby food contains added sugar. And all those additions can be troubling to your health, say experts. “Sugar is directly linked to obesity, tooth decay, diabetes, fatigue, headaches, arthritis, adrenal burnout and physiological or emotional problems such as ADHD and PMS,” says Dr. Steve Weston, Director of Ambassador Relations/Nutrition Expert of Sunwarrior, a producer of raw, plant-based supplements. For improved health, here are several ways to become more mindful about your sugar consumption: • There are many names and forms of sugar so learning to read food labels helps. Generally speaking, if an ingredient ends with the suffix -ose, then it’s a sugar. • Keep the sugar off the table and in the pantry. You’ll be less likely to add it to your meals. That being said, there are plenty of foods that you may be adding sugar to that are already sugary on their own -- from cereal to fresh fruit. Once you get used to the natural taste of these foods, you won’t miss the added spoonful. • Don’t use artificial sweeteners. While it may seem natural to reach for an artificial sweetener when you’re attempting to cut back on the real deal, it’s a grave mistake. Most artificial sweeteners actually increase cravings for sugary foods. If you do need a boost of sweetness, stick to more healthful whole food options, such as honey, date sugar, coconut sugar and pure organic maple syrup. • Seek out sweet flavors, while reaping the benefits of plant-based proteins with a protein blend such as Sunwarrior Protein, an easily digestible nutrient-filled superfood that tastes great and has zero grams of sugar and no unhealthy additives. “A healthy protein powder can ensure you’re getting a complete array of the essential amino acids needed to build and repair muscle, drive metabolism, keep skin young and elastic, build and balance hormones and carry out a host of other processes by allowing the body to create the right enzymes,” says Dr. Weston. Using low temperatures, enzymes, whole grains and superfoods, Sunwarrior’s unique process creates plant-based proteins that are silky smooth, mix well in smoothies, water, almond milk, coconut milk, shakes and other beverages, taste great and supply all the essential amino acids your body craves. More information can be found at www.Sunwarrior.com. • Pay attention to your skin, which is a reflection of your health and the quality of your nutrition. If you consume too much sugar, particularly from processed foods, a chemical reaction can form a rogue molecule known as an advanced glycation endproduct. Undesirable effects include wrinkles and droopy skin. By learning more about the foods you eat and making wise choices, you can reduce your sugar intake without missing out on flavor.
(StatePoint) Parents often wonder how to maintain their kids’ health. One important step that may be overlooked is to ensure that young children are properly hydrated. It can also be a challenge for parents to create a menu kids will enjoy that meets the recommended Daily Value (DV) of vitamins and nutrients. “By including U.S. Department of Agriculture (USDA)-certified organic fruits and vegetables in your children’s diets, you can help ensure your child is staying hydrated from the water in them, while also consuming the necessary vitamins, minerals and protein that they need to grow healthy and strong,” says Dr. Deena Blanchard, Pediatrician at Premier Pediatrics in New York City and a consultant for Ella’s Kitchen brand, which makes organic food for babies, toddlers and kids. “Nutritional shakes provide proteins, vitamins, and minerals, the necessary building blocks of a healthy immune system, to supplement kids’ daily diets for complete nutrition; and electrolyte waters with naturally-occurring electrolytes can also help keep kids hydrated.” Dr. Blanchard recommends the following tips to help parents make good choices for their children. • Hydrate children, especially when sick: When children are sick, the importance of proper hydration cannot be overestimated. If eating or drinking is difficult, try giving your child smaller amounts, more frequently. Choose water, 100 percent juice or drinks that contain naturally occurring electrolytes and other components that help support kids’ immune systems. • Choose wisely: Watch out for artificial flavors, colors and preservatives as well as the amount of added sugars in sports drinks and other beverages. It is important to provide kids with beverages that are free of artificial ingredients and contain fruits and vegetables. You can be sure you’re avoiding those additions when you choose USDA organic beverages, such as Ella’s Kitchen Organic Coconut Water Electrolyte Drinks or their new Smoothie Drinks, which provide one full serving of fruit per 8 fluid ounces. • Don’t forget to hydrate when playing sports: Kids can become dehydrated while playing sports or engaging in other physical activity. At the ballpark or playground, it is important to keep drinks on hand. Good choices include organic fruit and veggie purees, which contribute significant water to the diet and naturally-occurring electrolytes for natural rehydration. • Supplement: Though vital to proper growth and development, meeting the recommended daily intake of vitamins and nutrients can be tough, especially for little ones who are picky eaters. A tasty, protein-packed nutritional shake can help parents ensure kids get the calories and nutrition they need. Consider trying Ella’s Kitchen Coconut + Milk Nutritional Shakes, which are made with certified USDA organic low-fat milk, fruit + veggie purees and coconut water, providing 44 percent of the recommended DV of protein, 30 percent DV of calcium, as well as vitamin B12, riboflavin, iodine and electrolytes. Made with ingredients parents recognize, these shakes provide a boost of nutrition with a taste that kids will enjoy. Visit EllasKitchen.com for more options for healthy hydration and nutrition for the little ones. In the warmer months, proper hydration is especially crucial. Parents should seek out choices for kids that support a healthy immune system.
Newswise — ST. LOUIS — In research published inCancer Cell, Thomas Burris, Ph.D., chair of pharmacology and physiology at Saint Louis University, has, for the first time, found a way to stop cancer cell growth by targeting the Warburg Effect, a trait of cancer cell metabolism that scientists have been eager to exploit. Unlike recent advances in personalized medicine that focus on specific genetic mutations associated with different types of cancer, this research targets a broad principle that applies to almost every kind of cancer: its energy source. The Saint Louis University study, which was conducted in animal models and in human tumor cells in the lab, showed that a drug developed by Burris and colleagues at Scripps Research Institute can stop cancer cells without causing damage to healthy cells or leading to other severe side effects. The Warburg EffectMetabolism – the ability to use energy – is a feature of all living things. Cancer cells aggressively ramp up this process, allowing mutated cells to grow unchecked at the expense of surrounding tissue. “Targeting cancer metabolism has become a hot area over the past few years, though the idea is not new,” Burris said. Since the early 1900s, scientists have known that cancer cells prefer to use glucose as fuel even if they have plenty of other resources available. In fact, this is how doctors use PET (positron emission tomography) scan images to spot tumors. PET scans highlight the glucose that cancer cells have accumulated. This preference for using glucose as fuel is called the Warburg effect, or glycolysis. In his paper, Burris reports that the Warburg effect is the metabolic foundation of oncogenic (cancer gene) growth, tumor progression and metastasis as well as tumor resistance to treatment. Cancer’s Goal: To Grow and DivideCancer cells have one goal: to grow and divide as quickly as possible. And, while there are a number of possible molecular pathways a cell could use to find food, cancer cells have a set of preferred pathways. “In fact, they are addicted to certain pathways,” Burris said. “They need tools to grow fast and that means they need to have all of the parts for new cells and they need new energy.” “Cancer cells look for metabolic pathways to find the parts to grow and divide. If they don’t have the parts, they just die,” said Burris. “The Warburg effect ramps up energy use in the form of glucose to make chemicals required for rapid growth and cancer cells also ramp up another process, lipogenesis, that lets them make their own fats that they need to rapidly grow.” If the Warburg effect and lipogenesis are key metabolic pathways that drive cancer progression, growth, survival, immune evasion, resistance to treatment and disease recurrence, then, Burris hypothesizes, targeting glycolysis and lipogenesis could offer a way to stop a broad range of cancers. Cutting off the Energy SupplyBurris and his colleagues created a class of compounds that affect a receptor that regulates fat synthesis. The new compound, SR9243, which started as an anti-cholesterol drug candidate, turns down fat synthesis so that cells can’t produce their own fat. This also impacts the Warburg pathway, turning cancer cells into more normal cells. SR9243 suppresses abnormal glucose consumption and cuts off cancer cells’ energy supply. When cancer cells don’t get the parts they need to reproduce through glucose or fat, they simply die. Because the Warburg effect is not a feature of normal cells and because most normal cells can acquire fat from outside, SR9243 only kills cancer cells and remains non-toxic to healthy cells. The drug also has a good safety profile; it is effective without causing weight loss, liver toxicity, or inflammation. Promising ResultsSo far, SR9243 has been tested in cultured cancer cells and in human tumor cells grown in animal models. Because the Warburg pathway is a feature of almost every kind of cancer, researchers are testing it on a number of different cancer models. “It works in a wide range of cancers both in culture and in human tumors developing in animal models,” Burris said. “Some are more sensitive to it than others. In several of these pathways, cells had been reprogramed by cancer to support cancer cell growth. This returns the metabolism to that of more normal cells.” In human tumors grown in animal models, Burris said, “It worked very well on lung, prostate, and colorectal cancers, and it worked to a lesser degree in ovarian and pancreatic cancers.” It also seems to work on glioblastoma, an extremely difficult to treat form of brain cancer, though it isn’t able to cross the brain/blood barrier very effectively. The challenge for researchers in this scenario will be to find a way to allow the drug to cross this barrier, the body’s natural protection for the brain, which can make it difficult for drug treatments to reach their target. And, in even more promising news, it appears that when SR9243 is used in combination with existing chemotherapy drugs, it increases their effectiveness, in a mechanism apart from SR9243’s own cancer fighting ability. Other researchers on the study include Colin A. Flaveny, Kristine Griffett, Bahaa El-Dien M. El-Gendy, Melissa Kazantzis, Monideepa Sengupta, Antonio L. Amelio, Arindam Chatterjee, John Walker, Laura A. Solt and Theodore M. Kamenecka. Established in 1836, Saint Louis University School of Medicine has the distinction of awarding the first medical degree west of the Mississippi River. The school educates physicians and biomedical scientists, conducts medical research, and provides health care on a local, national and international level. Research at the school seeks new cures and treatments in five key areas: cancer, liver disease, heart/lung disease, aging and brain disease, and infectious diseases.
Top 5 Tips to Surviving Summer Barbeques … When You’re Allergic to Everything Hudson Allergy estimates that nearly 40% of their patients who come in thinking they may have allergies soon learn that their gut was right. With food allergies like wheat, dairy, soy, shellfish, fish, nuts, tree nuts and eggs, the “Big 8” make up 90% of all food related allergies. Once summer rolls around and outdoor parties are back on the weekend agenda, allergies to alcohol is also something that needs to be considered. Dr. Tim Mainardi advises patients on how to best manage their food related allergies and what that really means for their lifestyle. There are always more chances of coming into contact with an allergen when dining out and Summer BBQs are a potential landmine for food allergy sufferers. Even “safe foods” like burgers sans buns could be a trigger for those allergic to gluten because there may be bread fillers or specialty sauces in the mix. Cross contamination is another big issue for those with severe sensitivity. Dr. Mainardi advises all patients to be prepared before they get to the party. Get tested and talk with your allergist beforehand so you know what you can and cannot handle. Look for hints that you might not be able to eat or drink something like color, texture, or ingredients. Don’t be afraid to say a polite “No thank you” when offered a treat you just can’t stomach. When in doubt, pack a safe snack to nibble if you get desperate. Stick with the basics that you have consumed historically without a problem like protein, fruit, and veggies. About Hudson Allergy: Hudson Allergy is at the forefront of innovative care in allergy and immunology in New York City. They specialize in evaluating and testing for any allergy conditions including Skin Allergies, Food Allergies, Seasonal Allergies, Asthma, Drug & Medication Allergies and more. They also test with a variety of methods including different types of skin tests and food challenges. Their paperless office and soothing environment immediately put patients at ease and get them taken care of with little wait time.
NEW STUDY SHOWS THOSE WITH THE MUTATION ALSO HAVE HIGHER POSSIBILITY OF DEVELOPING SECOND BREAST CANCER
Women with Inherited KRAS-variant Mutation May Be at Increased Breast Cancer Risk Due to Acute Estrogen Withdrawal New Study Shows Those with the Mutation also Have Higher Possibility of Developing Second Breast Cancer UCLA study finds that acute estrogen withdrawal may increase breast cancer risk and predicts aggressive breast cancer in women with the inherited genetic mutation known as the KRAS-variant Women with the KRAS-variant with a prior history of breast cancer were also found to have up to a 12-fold increased risk of developing a new primary breast cancer Researchers hope further study will help to refine the best strategies for women with the KRAS-variant through informed decision making about estrogen management and personalized breast cancer care UCLA researchers have discovered that for women with a relatively common inherited mutation, known as the KRAS-variant, abrupt lowering of estrogen may increase their breast cancer risk and impact breast cancer biology. Scientists also found that women with the KRAS-variant are more likely to develop a second primary breast cancer independent of a first breast cancer. In a two-year study led by Dr. Joanne Weidhaas, UCLA Jonsson Comprehensive Cancer Center member and director of translational research at the David Geffen School of Medicine, data was analyzed from a group of more than 1,700 breast cancer patients who all submitted DNA samples to be tested for the inherited KRAS-variant. The study also included a group of women with the KRAS-variant who were cancer-free, as well as biological models to scientifically confirm the clinical findings. Results showed that acute estrogen withdrawal, as experienced after ovary removal, or with hormone replacement therapy discontinuation, and/or a low estrogen state were associated with breast cancer in women with the KRAS-variant. Acute estrogen withdrawal also triggered breast cancer formation in KRAS-variant biological models used in the study. Furthermore, Weidhaas' team found that up to 45 percent of breast cancer patients with the KRAS-variant went on to develop a second independent breast cancer, representing a 12-fold increased risk over breast cancer patients without the KRAS-variant. Prior research has shown the KRAS-variant, found in 1 out of 17 people, or 6 percent of the world's population, predicts an increased risk of various cancers, including breast cancer, and is found in up to 20 percent of newly diagnosed cancer patients. Additionally, a previous study found that women with the KRAS-variant are significantly more likely to develop both breast and ovarian cancer. "Although we had evidence that the KRAS-variant was a stronger predictor of cancer risk for women than men, we did not previously have a scientific explanation for this observation," said Weidhaas, a professor of radiation oncology. "This study's findings, showing that estrogen withdrawal can influence cancer risk for women with the KRAS-variant, begins to provide some answers." Though the findings run contrary to some past research suggesting that women on combination hormone replacement therapy are more likely to develop breast cancer, they are in agreement with follow-up studies that found estrogen alone may actually protect women from breast cancer. "The KRAS-variant may be a genetic difference that could actually help identify women who could benefit from continuing estrogen, or at a minimum, at least tapering it appropriately," said Weidhaas. "We hope that there are real opportunities to personalize risk reducing strategies for these women, through further defining the most protective estrogen management approaches, as well as by understanding the impact of different treatment alternatives at the time of a woman's first breast cancer diagnosis." The study was published in Cell Cycle on May 11, 2015. The research was supported by the National Cancer Institute and the work was done in collaboration with Mirakind, a non-profit organization. About UCLA's Jonsson Comprehensive Cancer Center UCLA's Jonsson Comprehensive Cancer Center has more than 450 researchers and clinicians engaged in disease research, prevention, detection, control, treatment and education. One of the nation's largest comprehensive cancer centers, the Jonsson center is dedicated to promoting research and translating basic science into leading-edge clinical studies. In July 2014, the Jonsson Cancer Center was named among the top 10 cancer centers nationwide by U.S. News & World Report, a ranking it has held for 14 years. For more information on the Jonsson Cancer Center, visit our website at http://www.cancer.ucla.edu.
The no-diet approach to weight control By adopting sensible eating habits and practicing portion control, you can eat nutritious foods so that you take in as many calories as you need to maintain your health and well-being at your ideal weight. Often, weight loss occurs on its own simply when you start making better food choices, such as avoiding processed foods, sugar-laden foods, white bread and pasta (substitute whole-grain varieties instead), foods with a high percentage of calories from fat, alcoholic drinks. While nothing is absolutely forbidden, when you do succumb to temptation, keep the portion size small and add a bit more exercise to your daily workout. By replacing some unwise food choices with healthy ones, you'll be cutting back on calories. If you add some moderate physical activity, you have the perfect weight-loss plan without the need for special or inconvenient (and often expensive) diet plans. An example of a successful no-diet weight loss program A 45-year-old woman complains that she has gradually put on 12 pounds over the past year. In the last month, she's faced a stressful work deadline and added another 4 pounds to her frame. This individual's goal is to lose the 16 pounds she has gained. Since her weight has been gradually increasing, she knows that she is consuming more calories than she is burning, especially with her sedentary job. She decides that a weight loss of 1 pound per week (equal to a deficit of about 3,500 calories, or cutting 500 calories per day) would be acceptable and would allow her to reach her goal in about four months. She decides to make some changes that will allow her to cut back an average of 250 calories per day. Skipping a large glass of sweetened iced tea will save about 200 calories. Substituting mineral water for the cola she regularly drinks during meetings can save another 150 calories. Foregoing her morning muffin snack (or eating only half a muffin) can also save 250 calories or more. To reach her goal of a 500-calorie-per-day savings, she adds some exercise. Getting up early for a 20-minute walk before work and adding a 10-minute walk during her lunch break add up to a half hour of walking per day, which can burn about 200 calories. On weekends, she plans to walk for 60 minutes one day and spend one hour gardening the next day for even greater calorie burning. If walking for 60 minutes is too much, two 30-minute walks one day would burn the same number of calories. Twice per week she plans to stop at the gym on the way home from work, even if only for a half hour of stationary cycling or swimming (each burning up to 250 calories). By making just some of the dietary cutbacks mentioned and starting some moderate exercise, this individual can easily "save" the 3,500 calories per week needed for a 1-pound weight loss, leading to a healthy rate of weight loss without extreme denial or deprivation. Furthermore, her changes in diet and lifestyle are small and gradual, modifications that she can maintain over time. Superfoods Quiz: Test Your Diet IQTake our Superfoods Quiz! Get to know how unprocessed, raw, organic foods and healthy drinks are rich in nutrients and dietary...learn more » Childhood Obesity Quiz: Test Your Medical IQChildhood obesity has reached epidemic proportions. Take the Childhood Obesity Quiz to test your knowledge of the facts and...learn more » Belly (Abdominal) Fat Quiz: Test Your Belly Fat IQDid you know there is a medical term for belly fat? Find out what it is and learn why getting rid of belly fat may be the best...learn more » Fat and Fats Quiz: Test Your Diet IQTake this online Fat & Fats Quiz to learn if you really are what you eat!...learn more » Food Portion Distortion Quiz: Test Your Diet IQAre your portions deceiving you? Take the Food Portion Distortion Quiz to find out how and why gigantic portions trick you into...learn more » Healthy Eating at Restaurants Pictures Slideshow: Don't Abandon Your DietSee how to recognize the dangers and stay on your healthy diet when eating out. Watch this slideshow to learn about healthy...learn more »
The American Medical Association today distanced itself from Republican hopeful Rand Paul, offering its support to anyone else interested in running for president. Dr. Pauls misinformed statements on the dangers of vaccination seem to suggest that we should use air quotes when calling him doctor, said an AMA spokesperson. The AMA also pointed to Pauls assertion that the Ebola virus is incredibly contagious and could spread at a cocktail party as yet another reason for their lack of interest in showing support for his candidacy.
Voice Dream, a read-aloud app used globally by more than 100 thousand individuals, has revolutionized how the visually-impaired and reading disabled are consuming information. The app reads books aloud to users which for those with visual impairments and reading disabilities, has enhanced their reading experiences significantly. Voice Dream Reader’s features are organized in an uncluttered, intuitive, highly usable way - thereby creating an unparalleled user-friendly experience. Voice Dream Reader includes a female U.S. English voice and nearly 100 additional paid voices in 20 languages. In addition to English, Voice Dream supports Mandarin Chinese, Japanese, Spanish, French, German, Italian, Swedish, Danish, Norwegian, Finnish, Dutch, Portuguese, Russian, Czech, Catalan, Polish, Turkish, Greek, and Arabic languages, among others. With the use of Foxit Software, a leading software provider of fast, affordable and secure PDF solutions, Voice Dream extracts text from PDF files and marks them as read while customers use the app. With collaboration from Foxit, Voice Dream is able take text from PDFs so they can be read aloud and highlight text as it is being read, an important feature for users with reading disabilities. Voice Dream also provides the following features for loading and managing reading material: • Text extraction from eBooks in DRM-free ePub format • Text extraction from plain text, MS Word, MS PowerPoint, Apple Pages, RTF and HTML files • DAISY 3.0 text-based eBooks • DAISY 2.02 audiobooks • Audiobooks as ZIP of MP3 files, such as LibriVox • Dropbox, Google Drive and Evernote integration • Load files using iTunes via USB or WiFi • Bookshare integration • Gutenberg integration for over 40,000 free eBooks • Pocket and Instapaper integration • Built-in Web Browser to extract text from Web pages • Copy-paste via clipboard • Text Editor • Language translation via Google Translate through in-app purchases • Folders for organizing content • Export full text to clipboard, printer, email, and other apps • Export highlighted text and notes to clipboard, printer, email and other apps • Open the original Web page in Safari if possible • Share what you’re listening with friends on Twitter, Facebook, SMS or email (iOS 6+) For listening to text, Voice Dream offers the following: • Remote control enabled Play-Pause • Remembers where you stopped in each book or article • Powerful personal pronunciation dictionary • Configurable default speech rate, volume and pitch for each voice • Shows elapsed time and remaining time • Sleep timer • Previous and next book or article • Rewind and fast forward by sentence, paragraph, page, chapter, 15, 30 and 60 seconds • Rewind and fast forward through your bookmarks and highlights • Change reading speed on the fly. 50-500 words per minute • Change TTS voice on the fly • Remembers the voice and speech rate used for each book or article • Playlist for listening to multiple articles back to backs • Continues reading when you exit the app or lock the screen For a visual interaction with text, Voice Dream features: • Blazing fast vertical scrolling in two modes: Free and page by page • Synchronized word and line highlighting plus options to disable • Full screen mode to hide the controls • Focused Reading Mode with reduced text area and auto-scrolling • Full-text search • Table of contents for ePub and DAISY books • Page numbers for PDF documents and DAISY books • Bookmarking • Highlighting and note taking • Customizable font and font size • Includes OpenDyslexia font • Preset light and dark color theme, plus a fully customizable color theme • Built-in dictionary Voice Dream, with the help of Foxit Software, has made millions of books, documents and PDFs accessible to individuals that never had access to these texts before. Both organizations are proud of the difference they have made in the lives of thousands through the services they provide.
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Kids with ASDs didn't change their sniff response when odors were unpleasant
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Study suggests non-genetic factors may be what increases risk
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But, due to aging population, actual number of cancer deaths is rising
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Study finds genes that determine eye color line up along ones tied to alcohol abuse
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WebMD explains how to talk to a sexual partner about your hep C. Plus, learn the best ways to protect them from catching the virus.